How does the particle size of pharmaceutical powders affect the bioavailability of drugs?
The particle size of pharmaceutical powders greatly affects drug bioavailability. This is mainly reflected in these aspects: Dissolution rate Smaller drug particles have a larger surface area. This speeds up their dissolution in body fluids. For low-solubility drugs (BCS Ⅱ/Ⅳ class), reducing the particle size can greatly increase their solubility. This speeds up the drug’s […]